1. Designs and implements biochemical and cellular assays to guide the target validation primarily in the areas of oncology, immunology and neurosciences;
2. Leads the design and implementation of screening strategies for Hit Identification through either High Throughput Screening or other technologies;
3. Provides leadership in developing innovative approaches to screening and hit triage;
4. Ensures hits are pharmacologically relevant by applying necessary validation assays;
5. Analyzes validation and screening data including presentation at program team meetings;
6. Works with other leaders in non-clinical R&D to design mechanisms of action studies for drug candidates;
7. Responsible for grow internal talents and capabilities through recruiting and mentoring
1. PhD in biochemistry, biophysics, cell biology, pharmacology or related areas with a minimal of 8 years of industry experience;
2. Strong expertise in in vitro profiling and pharmacology using biochemical, biophysical, and cell based methods in at least one of the three therapeutic areas: oncology, immunology and neurosciences.;
3. Record of success in assay development for Hit Identification using biochemical and cellular methods;
4. Demonstrated experience and expertise with Hit triage;
5. In-depth knowledge of entire drug discovery process;
6. Good communication skills and experience of working external collaborators.
一家大型制药集团，该集团产品主要集中在肿瘤，CNS，风湿免疫等领域；整个临床团队属于高大上的那种，多名华裔及海归，成员均来自500强，目前进入临床的项目大约10多个。该职位要求必须有巨头总部工作经验（欧美）
